Anti-Human ADRB3 Recombinant Antibody (SAA1577) (HB002013)

Name: Anti-Human ADRB3 Recombinant Antibody (SAA1577)
Brand: abinScience
SKU: HB002013
Price: 196 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HB002013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1577

Cible

Beta-3 adrenoreceptor, Beta-3 adrenoceptor, B3AR, ADRB3, Beta-3 adrenergic receptor, ADRB3R

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P13945

RRID

Anti-Human ADRB3 Antibody (SAA1577) (abinScience Cat# HB002013, RRID:AB_3727338)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Beta-3 adrenergic receptor (ADRB3) is a ~43 kDa protein. G protein-coupled receptor for catecholamines that couples to both G(s) and G(i) proteins, leading to either activation or inhibition of adenylate cyclase and cAMP-dependent pathway, respectively. The rank order of potency for physiological agonists is norepinephrine > epinephrine. Involved in the regulation of thermogenesis and lipolysis in brown and white adipose tissue, after coupling to G(s) proteins and stimulation of the cAMP-PKA axis. Also activates lipolytic process by coupling to G(i) proteins and consequent initiation of the ERK1/2 MAP kinase cascade. Participates in relaxation of the blood vessels and the urinary bladder.

1. Igawa, Y. et al. (1999) British journal of pharmacology 126, 819-25. PMID: 10188996

2. Emorine, LJ. et al. (1989) Science (New York, N.Y.) 245, 1118-21. PMID: 2570461

3. Candelore, MR. et al. (1996) Endocrinology 137, 2638-41. PMID: 8641219

4. Soeder, KJ. et al. (1999) The Journal of biological chemistry 274, 12017-22. PMID: 10207024

5. Gauthier, C. et al. (1998) The Journal of clinical investigation 102, 1377-84. PMID: 9769330

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ADRB3 Antibody (SAA1577)

Reférences

Fiche technique

Anti-Human ADRB3 Recombinant Antibody (SAA1577).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai