

| Numéro de catalogue | HB679014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human AGXT Polyclonal Antibody (HB679014) is a rabbit polyclonal antibody detecting AGXT in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human AGXT (Met1-Leu392). | ||||||||
| Cible | SPAT, Serine--pyruvate aminotransferase, AGXT, AGT1, Alanine--glyoxylate aminotransferase, AGT, SPT | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P21549 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Alanine--glyoxylate aminotransferase (AGXT) is a ~43 kDa protein. Peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification. Also catalyzes the transamination between L-serine and pyruvate and contributes to gluconeogenesis from the L-serine metabolism. 1. Lumb, MJ. et al. (2000) The Journal of biological chemistry 275, 36415-22. PMID: 10960483 2. Santana, A. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 7277-82. PMID: 12777626 3. Fargue, S. et al. (2013) The Journal of biological chemistry 288, 2475-84. PMID: 23229545 4. Oppici, E. et al. (2013) Biochimica et biophysica acta 1832, 2277-88. PMID: 24055001 5. Montioli, R. et al. (2015) Biochimica et biophysica acta 1854, 1280-9. PMID: 26149463 6. Xue, HH. et al. (1999) The Journal of biological chemistry 274, 16028-33. PMID: 10347152 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-AGXT polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse liver lysate
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