

| Numéro de catalogue | HV430014 | ||||||||
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| Description |
Anti-Human AHI1 Polyclonal Antibody (HV430014) is a rabbit polyclonal antibody detecting AHI1. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human AHI1 (Arg596-Ile917). | ||||||||
| Cible | AHI-1, AHI1, Abelson helper integration site 1 protein homolog, Jouberin | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q8N157 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | Jouberin (AHI1) is a ~137 kDa protein. Involved in vesicle trafficking and required for ciliogenesis, formation of primary non-motile cilium, and recruitment of RAB8A to the basal body of primary cilium. Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in neuronal differentiation. As a positive modulator of classical Wnt signaling, may play a crucial role in ciliary signaling during cerebellum embryonic development. 1. Lancaster, MA. et al. (2011) Nature medicine 17, 726-31. PMID: 21623382 | ||||||||
| Note | For research use only |
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