

| Número de catálogo | HF970014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human AHSA1 Polyclonal Antibody (HF970014) is a rabbit polyclonal antibody detecting AHSA1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human AHSA1 (His26-Ile164). | ||||||||
| Objetivo | Activator of 90 kDa heat shock protein ATPase homolog 1, AHA1, p38, AHSA1, C14orf3, HSPC322 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O95433 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Activator of 90 kDa heat shock protein ATPase homolog 1 (AHSA1) is a ~38 kDa protein. Acts as a co-chaperone of HSP90AA1. Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity. Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins. 1. Woodford, MR. et al. (2017) The EMBO journal 36, 3650-3665. PMID: 29127155 2. Woodford, MR. et al. (2016) Nature communications 7, 12037. PMID: 27353360 | ||||||||
| Nota | For research use only. |
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