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Anti-Human AKAP8L Polyclonal Antibody (HA275014)

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Vista general
Número de catálogoHA275014
Descripción
Anti-Human AKAP8L Polyclonal Antibody (HA275014) is a rabbit polyclonal antibody detecting AKAP8L in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human AKAP8L (Thr354-Gly565).
Objetivo Helicase A-binding protein 95, AKAP8L, Neighbor of AKAP95, Neighbor of A-kinase-anchoring protein 95, Homologous to AKAP95 protein, A-kinase anchor protein 8-like, AKAP8-like protein, HA95, NAKAP, NAKAP95, HAP95
Purificación Purified by antigen affinity column.
Número de acceso Q9ULX6
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

A-kinase anchor protein 8-like (AKAP8L) is a ~71 kDa protein. Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export. Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis.

1. Westberg, C. et al. (2000) The Journal of biological chemistry 275, 21396-401. PMID: 10748171
2. Yang, JP. et al. (2001) The Journal of biological chemistry 276, 30694-700. PMID: 11402034
3. Orstavik, S. et al. (2000) Biology of the cell 92, 27-37. PMID: 10761695
4. Han, I. et al. (2002) Molecular and cellular biology 22, 2136-46. PMID: 11884601
5. Martins, SB. et al. (2000) Journal of cell science 113 Pt 21, 3703-13. PMID: 11034899
6. Martins, S. et al. (2003) The Journal of cell biology 160, 177-88. PMID: 12538639
7. Li, Y. et al. (2006) Genes & development 20, 2566-79. PMID: 16980585
8. Kvissel, AK. et al. (2007) Experimental cell research 313, 2795-809. PMID: 17594903
Nota For research use only.
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human AKAP8L Polyclonal Antibody

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