Anti-Human AKAP8L Polyclonal Antibody (HA275014)

Name: Anti-Human AKAP8L Polyclonal Antibody
Brand: abinScience
SKU: HA275014
Price: 168 USD
Availability: InStock

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Fiche technique
SDS

Aperçu

Numéro de catalogue

HA275014

Description

Anti-Human AKAP8L Polyclonal Antibody (HA275014) is a rabbit polyclonal antibody detecting AKAP8L in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human, Mouse

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human AKAP8L (Thr354-Gly565).

Cible

Helicase A-binding protein 95, AKAP8L, Neighbor of AKAP95, Neighbor of A-kinase-anchoring protein 95, Homologous to AKAP95 protein, A-kinase anchor protein 8-like, AKAP8-like protein, HA95, NAKAP, NAKAP95, HAP95

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9ULX6

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

A-kinase anchor protein 8-like (AKAP8L) is a ~71 kDa protein. Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export. Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis.

1. Westberg, C. et al. (2000) The Journal of biological chemistry 275, 21396-401. PMID: 10748171

2. Yang, JP. et al. (2001) The Journal of biological chemistry 276, 30694-700. PMID: 11402034

3. Orstavik, S. et al. (2000) Biology of the cell 92, 27-37. PMID: 10761695

4. Han, I. et al. (2002) Molecular and cellular biology 22, 2136-46. PMID: 11884601

5. Martins, SB. et al. (2000) Journal of cell science 113 Pt 21, 3703-13. PMID: 11034899

6. Martins, S. et al. (2003) The Journal of cell biology 160, 177-88. PMID: 12538639

7. Li, Y. et al. (2006) Genes & development 20, 2566-79. PMID: 16980585

8. Kvissel, AK. et al. (2007) Experimental cell research 313, 2795-809. PMID: 17594903

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human AKAP8L Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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