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| カタログ番号 | HA275014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human AKAP8L Polyclonal Antibody (HA275014) is a rabbit polyclonal antibody detecting AKAP8L in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human AKAP8L (Thr354-Gly565). | ||||||||
| ターゲット | Helicase A-binding protein 95, AKAP8L, Neighbor of AKAP95, Neighbor of A-kinase-anchoring protein 95, Homologous to AKAP95 protein, A-kinase anchor protein 8-like, AKAP8-like protein, HA95, NAKAP, NAKAP95, HAP95 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9ULX6 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | A-kinase anchor protein 8-like (AKAP8L) is a ~71 kDa protein. Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export. Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA. May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis. 1. Westberg, C. et al. (2000) The Journal of biological chemistry 275, 21396-401. PMID: 10748171 2. Yang, JP. et al. (2001) The Journal of biological chemistry 276, 30694-700. PMID: 11402034 3. Orstavik, S. et al. (2000) Biology of the cell 92, 27-37. PMID: 10761695 4. Han, I. et al. (2002) Molecular and cellular biology 22, 2136-46. PMID: 11884601 5. Martins, SB. et al. (2000) Journal of cell science 113 Pt 21, 3703-13. PMID: 11034899 6. Martins, S. et al. (2003) The Journal of cell biology 160, 177-88. PMID: 12538639 7. Li, Y. et al. (2006) Genes & development 20, 2566-79. PMID: 16980585 8. Kvissel, AK. et al. (2007) Experimental cell research 313, 2795-809. PMID: 17594903 | ||||||||
| 注意事項 | For research use only. |
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