

| Numéro de catalogue | HW329014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ALDH1A3 Polyclonal Antibody (HW329014) is a rabbit polyclonal antibody detecting ALDH1A3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ALDH1A3 (Lys33-Pro512). | ||||||||
| Cible | Aldehyde dehydrogenase family 1 member A3, Aldehyde dehydrogenase 6, ALDH1A3, RalDH3, ALDH6, Retinaldehyde dehydrogenase 3, RALDH-3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P47895 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Retinaldehyde dehydrogenase 3 (ALDH1A3) is a ~56 kDa protein. Catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity. Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions; a critical lipid in the embryonic development of the eye and the nasal region. 1. Moretti, A. et al. (2016) Scientific reports 6, 35710. PMID: 27759097 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-ALDH1A3 polyclonal antibody at 1μg/ml on various samples.
Lane 1: A549 cell lysate
Lane 2: Mouse liver lysate
Lane 3: Mouse kidney lysate
Lane 4: Rat liver lysate
Lane 5: Rat kidney lysate
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