Anti-Human ALKBH4 Polyclonal Antibody (HP413014)

Name: Anti-Human ALKBH4 Polyclonal Antibody
Brand: abinScience
SKU: HP413014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HP413014

Описание

Anti-Human ALKBH4 Polyclonal Antibody (HP413014) is a rabbit polyclonal antibody detecting ALKBH4 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human ALKBH4 (Thr8-Val302).

Цель

ALKBH4, Lysine-specific demethylase ALKBH4, DNA N6-methyl adenine demethylase ALKBH4, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4, ABH4, Alkylated DNA repair protein alkB homolog 4

Очистка

Purified by antigen affinity column.

Номер доступа

Q9NXW9

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 (ALKBH4) is a ~33 kDa protein. Dioxygenase that mediates demethylation of actin monomethylated at 'Lys-84' (K84me1), thereby acting as a regulator of actomyosin-processes. Demethylation of actin K84me1 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. In addition to proteins, also demethylates DNA: specifically demethylates DNA methylated on the 6th position of adenine (N(6)-methyladenosine) DNA, thereby regulating Polycomb silencing.

1. Li, MM. et al. (2013) Nature communications 4, 1832. PMID: 23673617

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human ALKBH4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

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