Anti-Human ALKBH7 Polyclonal Antibody (HP973014)

Name: Anti-Human ALKBH7 Polyclonal Antibody
Brand: abinScience
SKU: HP973014
Price: 168 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HP973014

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human ALKBH7 (Ser16-Cys221).

Objetivo

Spermatogenesis-associated protein 11, ABH7, Alkylated DNA repair protein alkB homolog 7, ALKBH7, Spermatogenesis cell proliferation-related protein, SPATA11, Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial

Purificación

Purified by antigen affinity column.

Número de acceso

Q9BT30

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

RNA demethylase ALKBH7, mitochondrial is a ~24 kDa protein. RNA demethylase that demethylates N(2)-dimethylguanosine and N(1)-methyladenosine within mitochondrial pre-tRNA regions. This demethylation activity plays a crucial role in regulating the processing of nascent polycistronic mitochondrial RNA, thereby influencing mitochondrial gene expression and overall mitochondrial activity. In response to extensive DNA damage is required for programmed necrosis induced by alkylation and oxidation. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death. Involved in fatty acid metabolism.

1. Zhang, LS. et al. (2021) Nature cell biology 23, 684-691. PMID: 34253897

2. Fu, D. et al. (2013) Genes & development 27, 1089-100. PMID: 23666923

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-Human ALKBH7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo