

| Numéro de catalogue | HV443014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human AMACR (Ala2-Lys200). | ||||||||
| Cible | AMACR, Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9UHK6 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Alpha-methylacyl-CoA racemase (AMACR) is a ~42 kDa protein. Catalyzes the interconversion of (R)- and (S)-stereoisomers of alpha-methyl-branched-chain fatty acyl-CoA esters. Acts only on coenzyme A thioesters, not on free fatty acids, and accepts as substrates a wide range of alpha-methylacyl-CoAs, including pristanoyl-CoA, trihydroxycoprostanoyl-CoA (an intermediate in bile acid synthesis), and arylpropionic acids like the anti-inflammatory drug ibuprofen (2-(4-isobutylphenyl)propionic acid) but neither 3-methyl-branched nor linear-chain acyl-CoAs. 1. Ferdinandusse, S. et al. (2000) Nature genetics 24, 188-91. PMID: 10655068 2. Ferdinandusse, S. et al. (2000) Journal of lipid research 41, 1890-6. PMID: 11060359 3. Schmitz, W. et al. (1995) European journal of biochemistry 231, 815-22. PMID: 7649182 | ||||||||
| Note | For research use only. |



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