Anti-Human AMOTL2/LCCP Polyclonal Antibody (HP046014)

Name: Anti-Human AMOTL2/LCCP Polyclonal Antibody
Brand: abinScience
SKU: HP046014
Price: 168 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) :

Spécification :

50ug
100ug

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HP046014

Reactivité des espèces

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant Human AMOTL2/LCCP (Ser540-Asp653).

Cible

LCCP, AMOTL2, Angiomotin-like protein 2, Leman coiled-coil protein, KIAA0989

Purification

Purified by antigen affinity column.

Numéro d'accès

Q9Y2J4

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Angiomotin-like protein 2 (AMOTL2/LCCP) is a ~85 kDa protein. Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Plays a role in coupling actin fibers to cell junctions in endothelial cells and is therefore required for correct endothelial cell morphology via facilitating transcellular transmission of mechanical force resulting in endothelial cell elongation. Required for the anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane which facilitates organization of radial actin fiber structure and cellular response to contractile forces. This contributes to maintenance of cell area, size, shape, epithelial sheet organization and trophectoderm cell properties that facilitate blastocyst zona hatching.

1. Hildebrand, S. et al. (2017) Scientific reports 7, 9540. PMID: 28842668

2. Hwang, D. et al. (2021) Life science alliance 4. PMID: 34404733

3. Huang, H. et al. (2007) Development (Cambridge, England) 134, 979-88. PMID: 17293535

4. Zhao, B. et al. (2011) Genes & development 25, 51-63. PMID: 21205866

5. Kim, M. et al. (2016) EMBO reports 17, 64-78. PMID: 26598551

6. Lucci, V. et al. (2013) Gene 529, 300-6. PMID: 23911299

7. Proszynski, TJ. et al. (2013) Journal of cell science 126, 2225-35. PMID: 23525008

Note

For research use only.

Images

Reférences

Fiche technique

Anti-Human AMOTL2/LCCP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

Kits d'Essai