Anti-Human AMOTL2/LCCP Polyclonal Antibody (HP046014)

Name: Anti-Human AMOTL2/LCCP Polyclonal Antibody
Brand: abinScience
SKU: HP046014
Price: 168 USD
Availability: InStock

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HP046014

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human AMOTL2/LCCP (Ser540-Asp653).

Цель

LCCP, AMOTL2, Angiomotin-like protein 2, Leman coiled-coil protein, KIAA0989

Очистка

Purified by antigen affinity column.

Номер доступа

Q9Y2J4

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Angiomotin-like protein 2 (AMOTL2/LCCP) is a ~85 kDa protein. Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Plays a role in coupling actin fibers to cell junctions in endothelial cells and is therefore required for correct endothelial cell morphology via facilitating transcellular transmission of mechanical force resulting in endothelial cell elongation. Required for the anchoring of radial actin fibers to CDH1 junction complexes at the cell membrane which facilitates organization of radial actin fiber structure and cellular response to contractile forces. This contributes to maintenance of cell area, size, shape, epithelial sheet organization and trophectoderm cell properties that facilitate blastocyst zona hatching.

1. Hildebrand, S. et al. (2017) Scientific reports 7, 9540. PMID: 28842668

2. Hwang, D. et al. (2021) Life science alliance 4. PMID: 34404733

3. Huang, H. et al. (2007) Development (Cambridge, England) 134, 979-88. PMID: 17293535

4. Zhao, B. et al. (2011) Genes & development 25, 51-63. PMID: 21205866

5. Kim, M. et al. (2016) EMBO reports 17, 64-78. PMID: 26598551

6. Lucci, V. et al. (2013) Gene 529, 300-6. PMID: 23911299

7. Proszynski, TJ. et al. (2013) Journal of cell science 126, 2225-35. PMID: 23525008

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human AMOTL2/LCCP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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