

| Número de catálogo | HF867014 | ||||||||
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| Descripción |
Anti-Human AP2A1 Polyclonal Antibody (HF867014) is a rabbit polyclonal antibody detecting AP2A1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human AP2A1 (Ile737-Phe977). | ||||||||
| Objetivo | AP-2 complex subunit alpha-1, Alpha1-adaptin, Adaptor protein complex AP-2 subunit alpha-1, 100 kDa coated vesicle protein A, Clathrin assembly protein complex 2 alpha-A large chain, ADTAA, CLAPA1, AP2A1, Adaptor-related protein complex 2 subunit alpha-1, Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit, Alpha-adaptin A | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O95782 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | AP-2 complex subunit alpha-1 (AP2A1) is a ~107 kDa protein. Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. 1. Marcello, E. et al. (2013) The Journal of clinical investigation 123, 2523-38. PMID: 23676497 | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-AP2A1 polyclonal antibody at 1μg/ml on various samples.
Lane 1: SKOV3 cell lysate
Lane 2: THP-1 cell lysate
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