

| Numéro de catalogue | HT291013 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||
| Applications | Blocking, ELISA | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| ID de clone | 3.6D12 | ||||
| Cible | Apolipoprotein L1, ApoL-I, ApoL, APOL1, APOL, Apolipoprotein L-I, Apo-L, Apolipoprotein L, ApoL-II, Apolipoprotein L-II, APOL2, Apolipoprotein L2 | ||||
| Niveau d'endotoxines | < 10 EU/mg | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | O14791, Q9BQE5 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Apolipoprotein L1 (APOL1) is a ~43 kDa protein. May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in killing Trypanosoma brucei by forming pores in parasite lysosomal membranes and sensitizing T.brucei to oxidation-stimulated osmotic lysis. 1. Vanhamme, L. et al. (2003) Nature 422, 83-7. PMID: 12621437 2. Pérez-Morga, D. et al. (2005) Science (New York, N.Y.) 309, 469-72. PMID: 16020735 3. Lecordier, L. et al. (2009) PLoS pathogens 5, e1000685. PMID: 19997494 4. Greene, AS. et al. (2016) The Journal of biological chemistry 291, 3063-75. PMID: 26645690 5. Tytler, EM. et al. (1995) Molecular and biochemical parasitology 69, 9-17. PMID: 7723792 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human APOL1/Apolipoprotein?L1, L2 Antibody (3.6D12).
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