

| Numéro de catalogue | HT308014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human AQP7 Polyclonal Antibody (HT308014) is a rabbit polyclonal antibody detecting AQP7 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human AQP7 (Phe236-Phe342). | ||||||||
| Cible | Aquaporin-7, AQP-7, Aquaglyceroporin-7, Aquaporin adipose, AQPap, Aquaporin-7-like, AQP7, AQP7L, AQP9 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O14520 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Aquaporin-7 (AQP7) is a ~37 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Mediates the efflux of glycerol, formed upon triglyceride hydrolysis, to avoid its accumulation in adipocytes and to make it available to other tissues. In the kidney, mediates the reabsorption of glycerol, preventing its loss in urine, again participating to energy homeostasis. In pancreatic beta cells, it also mediates the efflux of glycerol, regulating its intracellular levels. 1. Kondo, H. et al. (2002) European journal of biochemistry 269, 1814-26. PMID: 11952783 2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639 3. Mósca, AF. et al. (2018) Cells 7. PMID: 30423801 4. Huang, P. et al. (2023) Nature communications 14, 600. PMID: 36737436 5. Kuriyama, H. et al. (1997) Biochemical and biophysical research communications 241, 53-8. PMID: 9405233 | ||||||||
| Note | For research use only. |
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