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Anti-Human AQP7 Polyclonal Antibody (HT308014)

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概要
カタログ番号HT308014
説明
Anti-Human AQP7 Polyclonal Antibody (HT308014) is a rabbit polyclonal antibody detecting AQP7 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
種反応性Human
アプリケーションELISA, IHC, WB
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 E. coli - derived recombinant Human AQP7 (Phe236-Phe342).
ターゲット Aquaporin-7, AQP-7, Aquaglyceroporin-7, Aquaporin adipose, AQPap, Aquaporin-7-like, AQP7, AQP7L, AQP9
精製 Purified by antigen affinity column.
アクセッション番号 O14520
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Aquaporin-7 (AQP7) is a ~37 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea. Mediates the efflux of glycerol, formed upon triglyceride hydrolysis, to avoid its accumulation in adipocytes and to make it available to other tissues. In the kidney, mediates the reabsorption of glycerol, preventing its loss in urine, again participating to energy homeostasis. In pancreatic beta cells, it also mediates the efflux of glycerol, regulating its intracellular levels.

1. Kondo, H. et al. (2002) European journal of biochemistry 269, 1814-26. PMID: 11952783
2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639
3. Mósca, AF. et al. (2018) Cells 7. PMID: 30423801
4. Huang, P. et al. (2023) Nature communications 14, 600. PMID: 36737436
5. Kuriyama, H. et al. (1997) Biochemical and biophysical research communications 241, 53-8. PMID: 9405233
注意事項 For research use only.
イメージ
参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
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Volume
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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