Anti-Human AQP8 Polyclonal Antibody (HC039014)

Name: Anti-Human AQP8 Polyclonal Antibody
Brand: abinScience
SKU: HC039014
Price: 168 USD
Availability: InStock

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SDS

Aperçu

Numéro de catalogue

HC039014

Description

Anti-Human AQP8 Polyclonal Antibody (HC039014) is a rabbit polyclonal antibody detecting Aquaporin-8; AQP-8; AQP8 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant human AQP8 (Glu58-Gly84&Lys129-Gly156&Ser205-Trp228).

Cible

Aquaporin-8; AQP-8; AQP8

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

O94778

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Aquaporin-8 (AQP8) is a ~27 kDa protein. Channel that allows the facilitated permeation of water and uncharged molecules, such as hydrogen peroxide and the neutral form of ammonia (NH3), through cellular membranes such as plasma membrane, inner mitochondrial membrane and endoplasmic reticulum membrane of several tissues. The transport of the ammonia neutral form induces a parallel transport of proton, at alkaline pH when the concentration of ammonia is high. However, it is unclear whether the transport of proton takes place via the aquaporin or via an endogenous pathway. Also, may transport ammonia analogs such as formamide and methylamine, a transport favourited at basic pH due to the increase of unprotonated (neutral) form, which is expected to favor diffusion. Does not transport urea or glycerol.

1. Liu, K. et al. (2006) Biology of the cell 98, 153-61. PMID: 15948717

2. Larocca, MC. et al. (2009) American journal of physiology. Gastrointestinal and liver physiology 296, G93-100. PMID: 18948439

3. Bertolotti, M. et al. (2013) Antioxidants & redox signaling 19, 1447-51. PMID: 23541115

4. Medraño-Fernandez, I. et al. (2016) Antioxidants & redox signaling 24, 1031-44. PMID: 26972385

5. Bestetti, S. et al. (2018) Science advances 4, eaar5770. PMID: 29732408

6. Danielli, M. et al. (2019) Free radical biology & medicine 131, 370-375. PMID: 30579780

Note

For research use only

Images

Reférences

Fiche technique

Anti-Human AQP8 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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