中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HC039014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human AQP8 Polyclonal Antibody (HC039014) is a rabbit polyclonal antibody detecting Aquaporin-8; AQP-8; AQP8 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||||
| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human AQP8 (Glu58-Gly84&Lys129-Gly156&Ser205-Trp228). | ||||||||
| ターゲット | Aquaporin-8; AQP-8; AQP8 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O94778 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Aquaporin-8 (AQP8) is a ~27 kDa protein. Channel that allows the facilitated permeation of water and uncharged molecules, such as hydrogen peroxide and the neutral form of ammonia (NH3), through cellular membranes such as plasma membrane, inner mitochondrial membrane and endoplasmic reticulum membrane of several tissues. The transport of the ammonia neutral form induces a parallel transport of proton, at alkaline pH when the concentration of ammonia is high. However, it is unclear whether the transport of proton takes place via the aquaporin or via an endogenous pathway. Also, may transport ammonia analogs such as formamide and methylamine, a transport favourited at basic pH due to the increase of unprotonated (neutral) form, which is expected to favor diffusion. Does not transport urea or glycerol. 1. Liu, K. et al. (2006) Biology of the cell 98, 153-61. PMID: 15948717 2. Larocca, MC. et al. (2009) American journal of physiology. Gastrointestinal and liver physiology 296, G93-100. PMID: 18948439 3. Bertolotti, M. et al. (2013) Antioxidants & redox signaling 19, 1447-51. PMID: 23541115 4. Medraño-Fernandez, I. et al. (2016) Antioxidants & redox signaling 24, 1031-44. PMID: 26972385 5. Bestetti, S. et al. (2018) Science advances 4, eaar5770. PMID: 29732408 6. Danielli, M. et al. (2019) Free radical biology & medicine 131, 370-375. PMID: 30579780 | ||||||||
| 注意事項 | For research use only |
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
