

| Numéro de catalogue | HX183014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ARF1 Polyclonal Antibody (HX183014) is a rabbit polyclonal antibody detecting ARF1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Catharanthus roseus.
Highlights
|
||||||||
| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ARF1 (Met1-Lys181). | ||||||||
| Cible | ADP-ribosylation factor 1, ARF1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P84077 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
||||||||
| Informations d'utilisation du produit |
| ||||||||
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | ADP-ribosylation factor 1 (ARF1) is a ~20 kDa protein. Small GTPase involved in protein trafficking between different compartments. Modulates vesicle budding and uncoating within the Golgi complex. In its GTP-bound form, triggers the recruitment of coatomer proteins to the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasticity of excitatory synapses and spine shrinkage during long-term depression (LTD). 1. Tanigawa, G. et al. (1993) The Journal of cell biology 123, 1365-71. PMID: 8253837 | ||||||||
| Note | For research use only. |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский