

| Каталожный номер | HX183014 | ||||||||
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| Описание |
Anti-Human ARF1 Polyclonal Antibody (HX183014) is a rabbit polyclonal antibody detecting ARF1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Catharanthus roseus.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human ARF1 (Met1-Lys181). | ||||||||
| Цель | ADP-ribosylation factor 1, ARF1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P84077 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | ADP-ribosylation factor 1 (ARF1) is a ~20 kDa protein. Small GTPase involved in protein trafficking between different compartments. Modulates vesicle budding and uncoating within the Golgi complex. In its GTP-bound form, triggers the recruitment of coatomer proteins to the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasticity of excitatory synapses and spine shrinkage during long-term depression (LTD). 1. Tanigawa, G. et al. (1993) The Journal of cell biology 123, 1365-71. PMID: 8253837 | ||||||||
| Примечание | For research use only. |
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