

| Número de catálogo | HX239014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ARF6 (Met1-Ser175). | ||||||||
| Objetivo | ARF6, ADP-ribosylation factor 6 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P62330 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | ADP-ribosylation factor 6 (ARF6) is a ~20 kDa protein. GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. GTP-bound form plays an important role in the transport of multiple palmitoylated proteins form the Golgi to the plasma membrane. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. 1. Pasqualato, S. et al. (2001) EMBO reports 2, 234-8. PMID: 11266366 2. Fang, Z. et al. (2006) Molecular & cellular proteomics : MCP 5, 1437-49. PMID: 16737952 3. Ha, VL. et al. (2008) The Journal of biological chemistry 283, 14915-26. PMID: 18400762 4. Selyunin, AS. et al. (2011) Nature 469, 107-11. PMID: 21170023 5. Kosciuk, T. et al. (2020) Nature communications 11, 1067. PMID: 32103017 6. D'Souza-Schorey, C. et al. (1995) Experimental cell research 221, 153-9. PMID: 7589240 7. Wang, J. et al. (2023) Journal of cell science 136. PMID: 37461827 8. Gauthier-Campbell, C. et al. (2004) Molecular biology of the cell 15, 2205-17. PMID: 14978216 9. Chau, DD. et al. (2022) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36, e22594. PMID: 36250347 10. Chen, KJ. et al. (2022) Journal of cell science 135. PMID: 36017701 | ||||||||
| Nota | For research use only. |
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