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| カタログ番号 | HX239014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ARF6 (Met1-Ser175). | ||||||||
| ターゲット | ARF6, ADP-ribosylation factor 6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P62330 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | ADP-ribosylation factor 6 (ARF6) is a ~20 kDa protein. GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling. GTP-bound form plays an important role in the transport of multiple palmitoylated proteins form the Golgi to the plasma membrane. Required for normal completion of mitotic cytokinesis. Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers. Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension. 1. Pasqualato, S. et al. (2001) EMBO reports 2, 234-8. PMID: 11266366 2. Fang, Z. et al. (2006) Molecular & cellular proteomics : MCP 5, 1437-49. PMID: 16737952 3. Ha, VL. et al. (2008) The Journal of biological chemistry 283, 14915-26. PMID: 18400762 4. Selyunin, AS. et al. (2011) Nature 469, 107-11. PMID: 21170023 5. Kosciuk, T. et al. (2020) Nature communications 11, 1067. PMID: 32103017 6. D'Souza-Schorey, C. et al. (1995) Experimental cell research 221, 153-9. PMID: 7589240 7. Wang, J. et al. (2023) Journal of cell science 136. PMID: 37461827 8. Gauthier-Campbell, C. et al. (2004) Molecular biology of the cell 15, 2205-17. PMID: 14978216 9. Chau, DD. et al. (2022) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36, e22594. PMID: 36250347 10. Chen, KJ. et al. (2022) Journal of cell science 135. PMID: 36017701 | ||||||||
| 注意事項 | For research use only. |
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