Anti-Human ARHGDIA Polyclonal Antibody (HW313014)

Name: Anti-Human ARHGDIA Polyclonal Antibody
Brand: abinScience
SKU: HW313014
Price: 96 USD
Availability: InStock

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Datasheet
SDS

Vista general

Número de catálogo

HW313014

Descripción

Anti-Human ARHGDIA Polyclonal Antibody (HW313014) is a rabbit polyclonal antibody detecting ARHGDIA in ELISA, IHC, WB. Suitable for Bovine, Human, Macaca fascicularis, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human ARHGDIA (Asn69-Asp204).

Objetivo

Rho GDP-dissociation inhibitor 1, GDIA1, Rho GDI 1, Rho-GDI alpha, ARHGDIA

Purificación

Purified by antigen affinity column.

Número de acceso

P52565

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Rho GDP-dissociation inhibitor 1 (ARHGDIA) is a ~23 kDa protein. Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation.

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-ARHGDIA polyclonal antibody at 1μg/ml on various samples.
Lane 1: HL-60 cell lysate
Lane 2: NIH3T3 cell lysate
Lane 3: Mouse lung lysate
Lane 4: Rat lung lysate

Referencias

Datasheet

Anti-Human ARHGDIA Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo