

| Numéro de catalogue | HA489014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ARHGEF12 Polyclonal Antibody (HA489014) is a rabbit polyclonal antibody detecting ARHGEF12 in ELISA, IHC, WB. Suitable for Mus musculus and Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ARHGEF12 (Asn366-Gly556). | ||||||||
| Cible | ARHGEF12 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9NZN5 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Noms alternatifs | Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEF, ARHGEF12 | ||||||||
| Contexte | Rho guanine nucleotide exchange factor 12 (ARHGEF12) is a ~173 kDa protein. Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Promotes endothelial cell and actin stress fiber reorientation in response to mechanotransduction. 1. Fukuhara, S. et al. (2000) FEBS letters 485, 183-8. PMID: 11094164 | ||||||||
| Note | For research use only. |
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