

| カタログ番号 | HA489014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Human ARHGEF12 Polyclonal Antibody (HA489014) is a rabbit polyclonal antibody detecting ARHGEF12 in ELISA, IHC, WB. Suitable for Mus musculus and Human.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human ARHGEF12 (Asn366-Gly556). | ||||||||
| ターゲット | ARHGEF12 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9NZN5 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 別名 | Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEF, ARHGEF12 | ||||||||
| 背景 | Rho guanine nucleotide exchange factor 12 (ARHGEF12) is a ~173 kDa protein. Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Promotes endothelial cell and actin stress fiber reorientation in response to mechanotransduction. 1. Fukuhara, S. et al. (2000) FEBS letters 485, 183-8. PMID: 11094164 | ||||||||
| 注意事項 | For research use only. |
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