

| Número de catálogo | HP257014 | ||||||||
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| Descripción |
Anti-Human ARHGEF25 Polyclonal Antibody (HP257014) is a rabbit polyclonal antibody detecting ARHGEF25 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ARHGEF25 (Ser149-Ser490). | ||||||||
| Objetivo | Rho guanine nucleotide exchange factor 25, p63RhoGEF, GEFT, Guanine nucleotide exchange factor GEFT, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT, Rac/Cdc42/Rho exchange factor GEFT, ARHGEF25 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q86VW2 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Rho guanine nucleotide exchange factor 25 (ARHGEF25) is a ~63 kDa protein. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. | ||||||||
| Nota | For research use only. |
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