

| Numéro de catalogue | HP257014 | ||||||||
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| Description |
Anti-Human ARHGEF25 Polyclonal Antibody (HP257014) is a rabbit polyclonal antibody detecting ARHGEF25 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ARHGEF25 (Ser149-Ser490). | ||||||||
| Cible | Rho guanine nucleotide exchange factor 25, p63RhoGEF, GEFT, Guanine nucleotide exchange factor GEFT, RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT, Rac/Cdc42/Rho exchange factor GEFT, ARHGEF25 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q86VW2 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Rho guanine nucleotide exchange factor 25 (ARHGEF25) is a ~63 kDa protein. May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation. May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. | ||||||||
| Note | For research use only. |
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