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Anti-Human ARL2 Polyclonal Antibody (HW643014)

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Vista general
Número de catálogoHW643014
Reactividad de especiesHuman, Mouse, Rat
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human ARL2 (Met1-Asp184).
Objetivo ARL2, ADP-ribosylation factor-like protein 2
Purificación Purified by antigen affinity column.
Número de acceso P36404
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

ADP-ribosylation factor-like protein 2 (ARL2) is a ~20 kDa protein. Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes.

1. Bhamidipati, A. et al. (2000) The Journal of cell biology 149, 1087-96. PMID: 10831612
2. Zhou, C. et al. (2006) Molecular biology of the cell 17, 2476-87. PMID: 16525022
3. Muromoto, R. et al. (2008) International immunology 20, 395-403. PMID: 18234692
4. Veltel, S. et al. (2008) FEBS letters 582, 2501-7. PMID: 18588884
5. Tian, G. et al. (2010) Cytoskeleton (Hoboken, N.J.) 67, 706-14. PMID: 20740604
6. Cai, XB. et al. (2019) Clinical genetics 96, 61-71. PMID: 30945270
Nota For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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