Anti-Human ASF1B IP Recombinant Antibody (SAA0242) (HP847013)

Name: Anti-Human ASF1B IP Recombinant Antibody (SAA0242)
Brand: abinScience
SKU: HP847013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HP847013

Reactividad de especies

Human

Aplicaciones

ELISA, IF, IP

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a

ID de clon

SAA0242

Objetivo

ASF1B, hAsf1, hCIA-II, CIA-II, hAsf1b, Histone chaperone ASF1B, Anti-silencing function protein 1 homolog B, CCG1-interacting factor A-II

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

Q9NVP2

RRID

Anti-Human ASF1B IP Antibody (SAA0242) (abinScience Cat# HP847013, RRID:AB_3729776)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Histone chaperone ASF1B is a ~22 kDa protein. Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' (H3K9me1) and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5K12ac) marks in the cytosol. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for gonad development.

1. Mello, JA. et al. (2002) EMBO reports 3, 329-34. PMID: 11897662

2. Tagami, H. et al. (2004) Cell 116, 51-61. PMID: 14718166

3. Groth, A. et al. (2005) Molecular cell 17, 301-11. PMID: 15664198

4. Tamburini, BA. et al. (2005) Eukaryotic cell 4, 1583-90. PMID: 16151251

5. Alvarez, F. et al. (2011) The Journal of biological chemistry 286, 17714-21. PMID: 21454524

6. Campos, EI. et al. (2015) Molecular cell 60, 697-709. PMID: 26527279

7. Campos, EI. et al. (2010) Nature structural & molecular biology 17, 1343-51. PMID: 20953179

8. Umehara, T. et al. (2003) The Journal of biological chemistry 278, 35660-7. PMID: 12842904

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human ASF1B IP Antibody (SAA0242)

Referencias

Datasheet

Anti-Human ASF1B IP Recombinant Antibody (SAA0242).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo