Anti-Human ASF1B IP Recombinant Antibody (SAA0242) (HP847013)

Name: Anti-Human ASF1B IP Recombinant Antibody (SAA0242)
Brand: abinScience
SKU: HP847013
Price: 191 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HP847013

Реактивность видов

Human

Применения

ELISA, IF, IP

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a

ID клона

SAA0242

Цель

ASF1B, hAsf1, hCIA-II, CIA-II, hAsf1b, Histone chaperone ASF1B, Anti-silencing function protein 1 homolog B, CCG1-interacting factor A-II

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

Q9NVP2

RRID

Anti-Human ASF1B IP Antibody (SAA0242) (abinScience Cat# HP847013, RRID:AB_3729776)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Histone chaperone ASF1B is a ~22 kDa protein. Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Also involved in the nuclear import of the histone H3-H4 dimer together with importin-4 (IPO4): specifically recognizes and binds newly synthesized histones with the monomethylation of H3 'Lys-9' (H3K9me1) and diacetylation at 'Lys-5' and 'Lys-12' of H4 (H4K5K12ac) marks in the cytosol. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for gonad development.

1. Mello, JA. et al. (2002) EMBO reports 3, 329-34. PMID: 11897662

2. Tagami, H. et al. (2004) Cell 116, 51-61. PMID: 14718166

3. Groth, A. et al. (2005) Molecular cell 17, 301-11. PMID: 15664198

4. Tamburini, BA. et al. (2005) Eukaryotic cell 4, 1583-90. PMID: 16151251

5. Alvarez, F. et al. (2011) The Journal of biological chemistry 286, 17714-21. PMID: 21454524

6. Campos, EI. et al. (2015) Molecular cell 60, 697-709. PMID: 26527279

7. Campos, EI. et al. (2010) Nature structural & molecular biology 17, 1343-51. PMID: 20953179

8. Umehara, T. et al. (2003) The Journal of biological chemistry 278, 35660-7. PMID: 12842904

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human ASF1B IP Antibody (SAA0242)

Ссылки

Даташит

Anti-Human ASF1B IP Recombinant Antibody (SAA0242).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа