Anti-Human ASPM Polyclonal Antibody (HA040014)

Name: Anti-Human ASPM Polyclonal Antibody
Brand: abinScience
SKU: HA040014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HA040014

Описание

Anti-Human ASPM Polyclonal Antibody (HA040014) is a rabbit polyclonal antibody detecting ASPM in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human ASPM (Ile159-Ser384).

Цель

MCPH5, Abnormal spindle-like microcephaly-associated protein, ASPM, Abnormal spindle protein homolog, Asp homolog

Очистка

Purified by antigen affinity column.

Номер доступа

Q8IZT6

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Abnormal spindle-like microcephaly-associated protein (ASPM) is a ~409 kDa protein. Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex. May have a preferential role in regulating neurogenesis.

1. Jiang, K. et al. (2017) Nature cell biology 19, 480-492. PMID: 28436967

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human ASPM Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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