

| Número de catálogo | HF560014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reactividad de especies | Human, Mouse | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ATG13 (Asp57-Arg190). | ||||||||
| Objetivo | ATG13, KIAA0652, Autophagy-related protein 13 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | O75143 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Autophagy-related protein 13 (ATG13) is a ~56 kDa protein. Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation. | ||||||||
| Nota | For research use only. |
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