Anti-Human ATG14 Polyclonal Antibody (HP189014)

Name: Anti-Human ATG14 Polyclonal Antibody
Brand: abinScience
SKU: HP189014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HP189014

説明

Anti-Human ATG14 Polyclonal Antibody (HP189014) is a rabbit polyclonal antibody detecting ATG14 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human ATG14 (Glu209-Glu415).

ターゲット

ATG14L, ATG14, Barkor, Atg14L, Beclin 1-associated autophagy-related key regulator, Autophagy-related protein 14-like protein, KIAA0831

精製

Purified by antigen affinity column.

アクセッション番号

Q6ZNE5

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Beclin 1-associated autophagy-related key regulator (ATG14) is a ~55 kDa protein. Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner.

1. Itakura, E. et al. (2008) Molecular biology of the cell 19, 5360-72. PMID: 18843052

2. Sun, Q. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 19211-6. PMID: 19050071

3. Matsunaga, K. et al. (2009) Nature cell biology 11, 385-96. PMID: 19270696

4. Matsunaga, K. et al. (2010) The Journal of cell biology 190, 511-21. PMID: 20713597

5. Fogel, AI. et al. (2013) Molecular and cellular biology 33, 3675-88. PMID: 23878393

6. Diao, J. et al. (2015) Nature 520, 563-6. PMID: 25686604

7. Shi, X. et al. (2023) Cell reports 42, 113045. PMID: 37632749

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-Human ATG14 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-Human ATG14 Polyclonal Antibody (HP189014)

概要

イメージ

参考文献

データシート

SDS