Anti-Human ATP6V0D1 Polyclonal Antibody (HX941014)

Name: Anti-Human ATP6V0D1 Polyclonal Antibody
Brand: abinScience
SKU: HX941014
Price: 96 USD
Availability: InStock

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Каталожный номер

HX941014

Описание

Anti-Human ATP6V0D1 Polyclonal Antibody (HX941014) is a rabbit polyclonal antibody detecting ATP6V0D1 in ELISA, IHC, WB. Suitable for Human, Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human ATP6V0D1 (Met1-Phe351).

Цель

V-ATPase AC39 subunit, V-ATPase subunit d 1, ATP6D, V-type proton ATPase subunit d 1, VPATPD, Vacuolar proton pump subunit d 1, ATP6V0D1, V-ATPase 40 kDa accessory protein, 32 kDa accessory protein, p39

Очистка

Purified by antigen affinity column.

Номер доступа

P61421

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

V-type proton ATPase subunit d 1 (ATP6V0D1) is a ~40 kDa protein. Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. May play a role in coupling of proton transport and ATP hydrolysis. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium.

1. Miles, AL. et al. (2017) eLife 6. PMID: 28296633

2. Jung, YS. et al. (2018) Nature cell biology 20, 1421-1433. PMID: 30374053

3. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human ATP6V0D1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human ATP6V0D1 Polyclonal Antibody (HX941014)

Обзор

Изображения

Ссылки

Даташит

SDS