

| Número de catálogo | HB838014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-Human ATP6V1C1 Polyclonal Antibody (HB838014) is a rabbit polyclonal antibody detecting ATP6V1C1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ATP6V1C1 (Lys156-Glu256). | ||||||||
| Objetivo | ATP6D, ATP6C, V-type proton ATPase subunit C 1, VATC, Vacuolar proton pump subunit C 1, ATP6V1C1, V-ATPase subunit C 1 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P21283 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | V-type proton ATPase subunit C 1 (ATP6V1C1) is a ~43 kDa protein. Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. 1. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002 | ||||||||
| Nota | For research use only. |

Western blot analysis was performed using anti-ATP6V1C1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
Lane 3: Rat kidney lysate



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