

| Каталожный номер | HB838014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-Human ATP6V1C1 Polyclonal Antibody (HB838014) is a rabbit polyclonal antibody detecting ATP6V1C1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human ATP6V1C1 (Lys156-Glu256). | ||||||||
| Цель | ATP6D, ATP6C, V-type proton ATPase subunit C 1, VATC, Vacuolar proton pump subunit C 1, ATP6V1C1, V-ATPase subunit C 1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P21283 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | V-type proton ATPase subunit C 1 (ATP6V1C1) is a ~43 kDa protein. Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. 1. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002 | ||||||||
| Примечание | For research use only. |

Western blot analysis was performed using anti-ATP6V1C1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse brain lysate
Lane 2: Rat brain lysate
Lane 3: Rat kidney lysate



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