

| Numéro de catalogue | HP356014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ATP6V1D Polyclonal Antibody (HP356014) is a rabbit polyclonal antibody detecting ATP6V1D in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ATP6V1D (Met1-Glu247). | ||||||||
| Cible | ATP6M, V-ATPase subunit D, Vacuolar proton pump subunit D, VATD, ATP6V1D, V-type proton ATPase subunit D, V-ATPase 28 kDa accessory protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9Y5K8 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | V-type proton ATPase subunit D (ATP6V1D) is a ~28 kDa protein. Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium. 1. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002 2. Chen, Y. et al. (2012) Cell research 22, 333-45. PMID: 21844891 | ||||||||
| Note | For research use only. |
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