

| Número de catálogo | HD677014 | ||||||||
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| Descripción |
Anti-Human ATRAID Polyclonal Antibody (HD677014) is a rabbit polyclonal antibody detecting ATRAID. Suitable for Human.
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human ATRAID (Leu31-Ser199). | ||||||||
| Objetivo | APR-3, APR3, ATRAID, All-trans retinoic acid-induced differentiation factor, Apoptosis-related protein 3, C2orf28, p18 | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q6UW56 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Fondo | All-trans retinoic acid-induced differentiation factor (ATRAID) is a ~24 kDa protein. Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol. 1. Yu, Z. et al. (2018) eLife 7. PMID: 29745899 | ||||||||
| Nota | For research use only |
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