

| Numéro de catalogue | HD677014 | ||||||||
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| Description |
Anti-Human ATRAID Polyclonal Antibody (HD677014) is a rabbit polyclonal antibody detecting ATRAID. Suitable for Human.
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ATRAID (Leu31-Ser199). | ||||||||
| Cible | APR-3, APR3, ATRAID, All-trans retinoic acid-induced differentiation factor, Apoptosis-related protein 3, C2orf28, p18 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q6UW56 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | All-trans retinoic acid-induced differentiation factor (ATRAID) is a ~24 kDa protein. Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol. 1. Yu, Z. et al. (2018) eLife 7. PMID: 29745899 | ||||||||
| Note | For research use only |
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