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Anti-Human B4GALT5 Polyclonal Antibody (HT475014)

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Vista general
Número de catálogoHT475014
Descripción
Anti-Human B4GALT5 Polyclonal Antibody (HT475014) is a rabbit polyclonal antibody detecting B4GALT5 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman, Mouse
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human B4GALT5 (Glu131-Tyr388).
Objetivo Beta-1, 4-galactosyltransferase 5, Beta-1, 4-GalTase 5, Beta4Gal-T5, b4Gal-T5, 2.4.1.-, Beta-1, 4-GalT II, Glucosylceramide beta-1, 4-galactosyltransferase, 2.4.1.274, Lactosylceramide synthase, LacCer synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 5, B4GALT5
Purificación Purified by antigen affinity column.
Número de acceso O43286
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Beta-1,4-galactosyltransferase 5 (B4GALT5) is a ~45 kDa protein. Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis.

1. Yamaji, T. et al. (2014) PloS one 9, e88124. PMID: 24498430
Nota For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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