

| Numéro de catalogue | HT475014 | ||||||||
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| Description |
Anti-Human B4GALT5 Polyclonal Antibody (HT475014) is a rabbit polyclonal antibody detecting B4GALT5 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human B4GALT5 (Glu131-Tyr388). | ||||||||
| Cible | Beta-1, 4-galactosyltransferase 5, Beta-1, 4-GalTase 5, Beta4Gal-T5, b4Gal-T5, 2.4.1.-, Beta-1, 4-GalT II, Glucosylceramide beta-1, 4-galactosyltransferase, 2.4.1.274, Lactosylceramide synthase, LacCer synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 5, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 5, B4GALT5 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O43286 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Beta-1,4-galactosyltransferase 5 (B4GALT5) is a ~45 kDa protein. Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis. 1. Yamaji, T. et al. (2014) PloS one 9, e88124. PMID: 24498430 | ||||||||
| Note | For research use only. |
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