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| カタログ番号 | HP632014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human B4GALT6 (Glu125-Tyr382). | ||||||||
| ターゲット | b4Gal-T6, Beta4Gal-T6, UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 6, Beta-1, 4-galactosyltransferase 6, Lactosylceramide synthase, UDP-Gal:glucosylceramide beta-1, 4-galactosyltransferase, Beta-1, 4-GalTase 6, Glucosylceramide beta-1, 4-galactosyltransferase, LacCer synthase, UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 6, B4GALT6 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9UBX8 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Beta-1,4-galactosyltransferase 6 (B4GALT6) is a ~44 kDa protein. Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. 1. Chatterjee, S. et al. (1992) The Journal of biological chemistry 267, 7148-53. PMID: 1551920 2. Yamaji, T. et al. (2014) PloS one 9, e88124. PMID: 24498430 3. Chatterjee, S. et al. (1987) Biochimica et biophysica acta 923, 136-42. PMID: 3099851 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-B4GALT6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
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