

| Número de catálogo | HA552014 | ||||||||
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| Descripción |
Anti-Human BAAT Polyclonal Antibody (HA552014) is a rabbit polyclonal antibody detecting BAAT in WB, IHC, ELISA. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | WB, IHC, ELISA | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human BAAT (Met1-Leu418). | ||||||||
| Objetivo | BAAT | ||||||||
| Nivel de endotoxinas | Please contact with the lab for this information. | ||||||||
| Pureza | >90% as determined by SDS-PAGE. | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q14032 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Nombres alternativos | Bile acid-CoA:amino acid N-acyltransferase, BACAT, BAT, EC:2.3.1.65, Bile acid-CoA thioesterase, Choloyl-CoA hydrolase, EC:3.1.2.27, Glycine N-choloyltransferase, Long-chain fatty-acyl-CoA hydrolase, EC:3.1.2.2, BAAT | ||||||||
| Fondo | Bile acid-CoA:amino acid N-acyltransferase (BAAT) is a ~46 kDa protein. Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine. More than 95% of the BAs are N-acyl amidates with glycine and taurine. Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism. This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption. May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids. 1. Sfakianos, MK. et al. (2002) The Journal of biological chemistry 277, 47270-5. PMID: 12239217 2. O'Byrne, J. et al. (2003) The Journal of biological chemistry 278, 34237-44. PMID: 12810727 3. Johnson, MR. et al. (1991) The Journal of biological chemistry 266, 10227-33. PMID: 2037576 4. Falany, CN. et al. (1994) The Journal of biological chemistry 269, 19375-9. PMID: 8034703 | ||||||||
| Nota | For research use only. |
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