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| カタログ番号 | HP608013 | ||||
|---|---|---|---|---|---|
| 説明 |
Anti-Human BAZ2B IP Recombinant Antibody (SAA0244) (HP608013) is a mouse monoclonal antibody detecting BAZ2B in ELISA, IF, IP, IP-MS. Suitable for Human.
Highlights
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| 種反応性 | Human | ||||
| アプリケーション | ELISA, IF, IP, IP-MS | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA0244 | ||||
| ターゲット | hWALp4, BAZ2B, Bromodomain adjacent to zinc finger domain protein 2B, KIAA1476 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | Q9UIF8 | ||||
| RRID | Anti-Human BAZ2B IP Antibody (SAA0244) (abinScience Cat# HP608013, RRID:AB_3729778) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) is a ~240 kDa protein. Regulatory subunit of the ATP-dependent BRF-1 and BRF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. The BRF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the BRF-5 ISWI chromatin remodeling complex. Chromatin reader protein, which may play a role in transcriptional regulation via interaction with ISWI. Involved in positively modulating the rate of age-related behavioral deterioration. 1. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535 2. Jones, MH. et al. (2000) Genomics 63, 40-5. PMID: 10662543 | ||||
| 注意事項 | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |
SDS-PAGE for Anti-Human BAZ2B IP Antibody (SAA0244).
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