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Anti-Human BCR Recombinant Antibody (SAA1570) (HY023013)

Anti-Human BCR Recombinant Antibody (SAA1570)
Anti-Human BCR Recombinant Antibody (SAA1570)
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Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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  • Datasheet

  • SDS

Vista general
Número de catálogoHY023013
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA1570
Objetivo Renal carcinoma antigen NY-REN-26, BCR1, BCR, D22S11, Breakpoint cluster region protein
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P11274
RRID Anti-Human BCR Antibody (SAA1570) (abinScience Cat# HY023013, RRID:AB_3727331)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Breakpoint cluster region protein (BCR) is a ~142 kDa protein. Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form.

1. Cho, YJ. et al. (2007) Molecular and cellular biology 27, 899-911. PMID: 17116687
2. Diekmann, D. et al. (1991) Nature 351, 400-2. PMID: 1903516
3. Chuang, TH. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 10282-6. PMID: 7479768
4. Dubash, AD. et al. (2013) The Journal of cell biology 202, 653-66. PMID: 23940119
5. Maru, Y. et al. (1991) Cell 67, 459-68. PMID: 1657398
Nota For research use only.
Imágenes
  • Anti-Human BCR Recombinant Antibody (SAA1570)

    SDS-PAGE

    SDS-PAGE for Anti-Human BCR Antibody (SAA1570)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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