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Anti-Human BCR Recombinant Antibody (SAA1570) (HY023013)

Anti-Human BCR Recombinant Antibody (SAA1570)
Anti-Human BCR Recombinant Antibody (SAA1570)
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  • 1mg
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Aperçu
Numéro de catalogueHY023013
Reactivité des espècesHuman
ApplicationsELISA
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG2a, kappa
ID de cloneSAA1570
Cible Renal carcinoma antigen NY-REN-26, BCR1, BCR, D22S11, Breakpoint cluster region protein
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P11274
RRID Anti-Human BCR Antibody (SAA1570) (abinScience Cat# HY023013, RRID:AB_3727331)
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:2000-1:20000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Contexte

Breakpoint cluster region protein (BCR) is a ~142 kDa protein. Protein with a unique structure having two opposing regulatory activities toward small GTP-binding proteins. The C-terminus is a GTPase-activating protein (GAP) domain which stimulates GTP hydrolysis by RAC1, RAC2 and CDC42. Accelerates the intrinsic rate of GTP hydrolysis of RAC1 or CDC42, leading to down-regulation of the active GTP-bound form. The central Dbl homology (DH) domain functions as guanine nucleotide exchange factor (GEF) that modulates the GTPases CDC42, RHOA and RAC1. Promotes the conversion of CDC42, RHOA and RAC1 from the GDP-bound to the GTP-bound form.

1. Cho, YJ. et al. (2007) Molecular and cellular biology 27, 899-911. PMID: 17116687
2. Diekmann, D. et al. (1991) Nature 351, 400-2. PMID: 1903516
3. Chuang, TH. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 10282-6. PMID: 7479768
4. Dubash, AD. et al. (2013) The Journal of cell biology 202, 653-66. PMID: 23940119
5. Maru, Y. et al. (1991) Cell 67, 459-68. PMID: 1657398
Note For research use only.
Images
  • Anti-Human BCR Recombinant Antibody (SAA1570)

    SDS-PAGE

    SDS-PAGE for Anti-Human BCR Antibody (SAA1570)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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