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| カタログ番号 | HB935117 |
|---|---|
| 種反応性 | Human |
| アプリケーション | ELISA, FCM |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2a, lambda |
| クローンID | SAA0471 |
| 抱合 | FITC |
| ターゲット | ProBDNF, Abrineurin, Brain-derived neurotrophic factor, BDNF |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 関連製品 | Mouse IgG2a Recombinant Isotype Control Antibody (C1.18.4), FITC |
| アクセッション番号 | P23560 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 背景 | Neurotrophic factor BDNF precursor form is a ~27 kDa protein. Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. 1. Mowla, SJ. et al. (2001) The Journal of biological chemistry 276, 12660-6. PMID: 11152678 |
| 注意事項 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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