Anti-Human BIN1 Recombinant Antibody (SAA1499) (HT430013)

Name: Anti-Human BIN1 Recombinant Antibody (SAA1499)
Brand: abinScience
SKU: HT430013
Price: 196 USD
Availability: InStock

Datasheet Compartir producto Copiar información

Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HT430013

Reactividad de especies

Human

Aplicaciones

ELISA

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA1499

Objetivo

AMPHL, Myc box-dependent-interacting protein 1, Amphiphysin II, Amphiphysin-like protein, Box-dependent myc-interacting protein 1, Bridging integrator 1, BIN1

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

O00499

RRID

Anti-Human BIN1 Antibody (SAA1499) (abinScience Cat# HT430013, RRID:AB_3727260)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Myc box-dependent-interacting protein 1 (BIN1/Amphiphysin-II) is a ~64 kDa protein. Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling. Is a negative regulator of endocytosis. Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production. In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates.

1. Wu, T. et al. (2014) PloS one 9, e93060. PMID: 24755653

2. Miyagawa, T. et al. (2016) Human molecular genetics 25, 2948-2958. PMID: 27179792

3. Sakamuro, D. et al. (1996) Nature genetics 14, 69-77. PMID: 8782822

4. Dräger, NM. et al. (2017) EMBO reports 18, 2051-2066. PMID: 28893863

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Human BIN1 Antibody (SAA1499)

Referencias

Datasheet

Anti-Human BIN1 Recombinant Antibody (SAA1499).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo