

| Numéro de catalogue | HY077013 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||
| Applications | ELISA | ||||
| Espèce hôte | Mouse | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG2a, kappa | ||||
| ID de clone | SAA1793 | ||||
| Cible | PCOLC, Mammalian tolloid protein, mTld, Bone morphogenetic protein 1, PCP, BMP-1, Procollagen C-proteinase, BMP1 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | P13497 | ||||
| RRID | Anti-Human BMP1 Antibody (SAA1793) (abinScience Cat# HY077013, RRID:AB_3727555) |
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| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Contexte | Bone morphogenetic protein 1 (BMP1) is a ~111 kDa protein. Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins. Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair. Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers. Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation. 1. N'Diaye, EN. et al. (2021) American journal of physiology. Cell physiology 320, C162-C174. PMID: 33206546 2. Anastasi, C. et al. (2020) Science signaling 13. PMID: 32636307 3. Wang, J. et al. (2021) Journal of periodontology 92, 1018-1029. PMID: 33169406 4. Rosell-García, T. et al. (2019) The Journal of biological chemistry 294, 11087-11100. PMID: 31152061 | ||||
| Note | For research use only. |

SDS-PAGE for Anti-Human BMP1 Antibody (SAA1793)
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